We will all need to find functions again. Code signatures and hooks will need to be rewritten. 'Plugins using the Address Library will need to be divided in to 'pre-AE' and 'post-AE' eras. 'This changes the way that the code is generated in a way that forces mod developers to start from scratch finding functions and writing hooks.
'Bethesda has decided to update the compiler used to build the 64-bit version of Skyrim from Visual Studio 2015 to Visual Studio 2019,' explains one of the SKSE developers on Reddit. This will have a major impact on mods using the SKSE. However, as reported by PC Gamer, rather than releasing the game as its own version on Steam, the Anniversary Edition will be available as an update to the existing entry. The Anniversary Edition release includes the Special Edition version of the game along with all mods available in the Creation Club and more yet to be announced.